Biomedical clean rooms are energy-intensive and highly complex air-conditioning systems, and they usually operate 24 hours a day throughout the year. Therefore, in order to achieve the environmental parameter targets required by the design, the energy consumption problem is more complicated. If we can have both, it will not consume too much energy. And economical and efficient operation will help save energy and the environment. However, only a very small number of research data and measurement studies on energy-saving systems and indoor environmental quality have been integrated. Therefore, this study will use field measurement data to evaluate the energy-saving feasibility of the air conditioning system in biomedical clean rooms, and conduct on-site measurements and numerical simulations for the vaccine cold storage room in biological clean rooms. The results showed that the energy-saving strategy based on the computer simulation improvement and measurement analysis results is feasible. In the vaccine cold room, the energy-saving strategy of using different air supply air volumes and changing the air supply temperature, through transient computer simulation of air flow distribution, can be achieved without affecting the vaccine. The feasibility of energy saving can also be achieved under the storage temperature specification of 0 ~ 4℃. This study can provide an important reference for the overall consideration of infection control, energy saving and environmental comfort in biomedical clean rooms.
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